Monday, June 29, 2009

TCA cycle by mnemonics.... its fun...

i'll present another mnemonic.. very fine one that i came up with... ( that should be decided by you)...
Citric acid cycle ....
citric acid ---> cis-aconitic acid----> isocitric acid--(NAD ---> NADH2) --> oxalosuccinic acid (OSA) --> alpha-ketoglutaric acid (@-KGA)
--(NAD --->NADH2)-> succinyl coA ,---> succinic acid ------> fumaric acid ------> malic acid --(NAD--->NADH2)--> oxalo acetic acid (OAA)----> again citric acid....
and to complicate things ( not actually !!!) in some steps NADH2 is formed, and in some FADH2 is formed.....
so.. here is my mnemonic...
Commonly, All sisters Isolate OSAma's KG- amputates Sharply Suceeding in Filming Meteorates (actually meteorites) Ascending only above...
now..plzz note that whenver a word ends with -ate here, in that step, NADH2 is formed.....that
here... Commonly - citric acid
All sisters = aconitic acid cis form
Isolate - isocitric acid....
OSAma = oxalosuccinic acid
KG-amputate = @-KGA
Sharply= succinyl coA
suceeding = succinic acid
filming = fumaric acid...
metoerate = malic acid

only ascending above = OAA

hope it helps...

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